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Researchers get first complete look at protein behind sense of touch

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Scientists at The Scripps Research Institute (TSRI) have solved the mystery of the structure of Piezo1, a member of a family of proteins that convert physical stimuli such as touch or blood flow into chemical signals. The findings, published today in the journal Nature, point the way to targeting diseases where Piezo1 is mutated, such as dehydrated hereditary stomatocytosis and congenital lymphedema.

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